Jan 04, 2026
Slc22a17 governs postnatal neurogenesis by maintaining the iron homeostasis in hippocampus | Prof. Ligong Chen
Iron transporters are essential for numerous iron-dependent biological processes. Among them, SLC22A17 plays a key role in lipocalin-2 (LCN2)-mediated iron transport and is implicated in several human diseases. However, its precise molecular and physiological functions remain poorly understood. In this study, we demonstrate that Slc22a17 is critical for postnatal neurogenesis through its regulation of iron homeostasis in the hippocampus.
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