The Landscape of Medical AI in China | Prof. Wong Tien Yin

China has achieved significant progress in the medical AI field in recent years. However, the international community may be unaware of the scope and extent of medical AI innovations in China. In this perspective, we provide data on the landscape of medical AI in China, covering research focus areas, key players from academia and industry, and the main drivers of medical AI development.

Myopia and high myopia trends in Chinese children and adolescents over 25years: a nationwide study with projections to 2050|Prof. Wong Tien Yin

The global rise in myopia, particularly in Asia, presents significant public health challenges. Analyzing trends and forecasting impacts are critical for developing strategies to mitigate this burden.

An organoid co-culture model for probing systemic anti-tumor immunity in lung cancer|A/Prof. Peng Liu

Deciphering interactions between tumor micro- and systemic immune macroenvironments is essential for developing more effective cancer diagnosis and therapeutic strategies. Here, we established a gel-liquid interface (GLI) co-culture model of lung cancer organoids (LCOs) and paired peripheral-blood mononuclear cells (PBMCs), featuring enhanced interactions between immune cells and tumor organoids for optimized simulation of in vivo systemic anti-tumor immunity.

EGR2 O-GlcNAcylation Orchestrates the Development of Protumoral Macrophages to Limit CD8+ T Cell Antitumor Responses|Prof. Hang Yin

Silicon-Rhodamine-Catalyzed Near-Infrared Light-Induced Photodecaging of Ortho-Nitrobenzyl Groups In Vitro and In Vivo|A/Prof. Ling Chu

High-resolution transcriptome atlas of bladder cancer highlights the functional myeloid subsets in modulating immune microenvironment |Prof. Li Wu

CREPT is required for the metastasis of triple-negative breast cancer through a co-operational-chromatin loop-based gene regulation |Prof. Zhijie Chang

Membrane-IL12 adjuvant mRNA vaccine polarizes pre-effector T cells for optimized tumor control |Prof. Yangxin Fu and Dr. Yong Liang

Clinical investigation on nebulized human umbilical cord MSC-derived extracellular vesicles for pulmonary fibrosis treatment |Prof. Zhijie Chang

TIM3-blockade synergizes with IL2 in alleviating intra-tumoral CD8+T cell exhaustion |Prof. Yangxin Fu