WU,Longyan-School of Medicine, Tsinghua University

Research Faculty

WU,Longyan

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    2000 – 2004 B.S., Biotechnology,School of Life Science, Northeast Normal University，Changchun, Jilin, China

    2004 – 2010 M.D., Pharmacy, School of Pharmacy, Shandong University, Ji’nan, Shandong, China

    2011 –2015 Postdoctoral Fellow, School of Medicine, Tsinghua University, Beijing, China

    2015 –presentResearch-trackAssistant Professor,School of Medicine, Tsinghua University, Beijing, China

The humoral immune response

1.Yan H*,Wu L*, Shih C, Hou S, Shi J, Mao T, Chen W, Melvin B, Rigby R.J., Chen Y, Jiang H, Friedel R, Vinuesa C, Qi H#. Plexin B2 and Semaphorin 4C guide T-cell recruitment and function in the germinal center.Cell Reports. 2017 May 2;19(5):995-1007.

2.Chen X*#, Ma W*, Zhang T,Wu L, Qi H#. Phenotypic Tfh development promoted by CXCR5-controlled re-localization and IL-6 from radiation-resistant cells.Protein & Cell.2015 Nov; 6(11): 825–32.

3.Ma W*#, Zhao R*, Yang R, Liu B, Chen X,Wu L, Qi H#. Nuclear receptors of the NR4A family are not required for the development and function of follicular T helper cells.Int. Immunopharmacol. 2015 Oct;28(2):841-5.

4.Chu C, Wang Y, Zhang X, Ni X, Cao J, Xu W, Dong Z, Yuan P, Wei W, Ma Y, Zhang L,Wu L, Qi H#. SAP-Regulated T Cell-APC Adhesion and Ligation-Dependent and -Independent Ly108-CD3ζ Interactions.J Immunol.2014 Oct 15;193(8):3860-71.

5.Wu L, Lu P, Ma W, Chu C, Xu H, Qi H#.Identification of a new isoform of the murine Sh2d1a gene and its functional implications.SciChina Life Sci.2014. 57(1):81-7.

6.Wu L, Zhang C, Tian Z, Zhang J#. NK cell-based approach for screening novel functional immune genes.Int. Immunopharmacol. 2011. 11(2):274-279.

7.Wu L, Zhang C, Zhang J#. HMBOX1 negatively regulates NK cell functions by suppressing the NKG2D/DAP10 signaling pathway.Cell. Mol. Immunol.2011. 8(5):433-440.

8.Wu L, Zhang C, Zheng X, Tian Z, Zhang J#. HMBOX1, homeobox transcription factor, negatively regulates interferon-γ production in natural killer cells.Int. Immunopharmacol. 2011. 11(11):1895-1900.