2015-2020 Postdoctoral Research Fellow, School of Medicine, Tsinghua University
2020-2024 Research Assistant Professor, School of Medicine, Tsinghua University
2024-present Research Associate Professor, School of Basic Medical Sciences, Tsinghua Medicine, Tsinghua University
The induction of adaptive immune memory is important for pathogen defense and is the primary goal of vaccine development. However, it also plays a major role in the pathogenesis of allergic and autoimmune diseases. Through the analyses of novel mouse models and clinical samples, we aim to understand the regulatory mechanisms underlying the differentiation, maintenance, and function of adaptive immune memory cells, in order to facilitate the rational design of vaccines and the development of novel therapeutic strategies for inflammatory diseases.
2024 Excellent Young Scientist Fund, National Science Foundation of China
2015 International postdoctoral exchange program, Tsinghua University, Beijing, China
1. Feng Lan*, Jizhou Li*, Wenxuan Miao*, Fei Su*, Su Duan, Yabing Song, Jiacheng Yao, Xiangdong Wang, Chengshuo Wang, Xin Liu#, Jianbin Wang#, Luo Zhang# and Hai Qi#. GZMK-expressing CD8 T cells promote recurrent airway inflammatory diseases, Nature, 2025. (#Co-corresponding author)
2. Yifeng Wang*, Wen Shao*, Xin Liu, Qingtai Liang, Jiaqi Lei, Wenjuan Shi, Miao Mei, Ying Li, Xu Tan, Guocan Yu, Li Yu, Linqi Zhang, Hai Qi#. High recallability of memory B cells requires ZFP318-dependent transcriptional regulation of mitochondrial function, Immunity, 57(8):1848-1863, 2024.
3. Xin Liu, Bo Liu, Hai Qi#. Germinal center reaction and output: recent advances. Current Opinion in Immunology, 82:102308, 2023.
4. Xin Liu*, Jiacheng Yao*, Yongshan Zhao, Jianbin Wang#, Hai Qi#. Heterogeneous plasma cells and long-lived subsets in response to immunization, autoantigen and microbiota. Nature Immunology, 23(11): 1564-1576, 2022.
5. Xin Liu#, Yongshan Zhao, Hai Qi#. T-independent antigen induces humoral memory through germinal centers. Journal of Experimental Medicine, 219(3): e20210527, 2022. (#Co-corresponding author)
