Home / About TM / Current Leadership / Content

WONG Tien Yin

Senior Vice-Chancellor

MBBS, MMed (Ophth), MPH, PhD, FRCSE, FRANZCO, FRCOph, FAHMS, FAMS

Founding Head and Chair Professor, Tsinghua Medicine

Vice Provost, Tsinghua University

Senior Advisor, SingHealth & Singapore National Eye Centre, Singapore

E-mail: wongtienyin@tsinghua.edu.cn

  • Education and Training

  • Leadership Appointment

  • Academic & Clinical Focus

  • Other Information

  • Publications

Prof Wong completed medical school (MBBS) at the National University of Singapore (NUS) as a President's Scholar. He obtained an MPH and PhD from the Johns Hopkins University, Baltimore, USA and received clinical training in ophthalmology at the Singapore National Eye Centre (SNEC), with retinal fellowships at the University of Wisconsin, Madison, USA and the University of Sydney, Australia.

In 2022, Prof Wong was appointed the Founding Head and Chair Professor of Tsinghua Medicine, a new academic health system based at Tsinghua University, Beijing, China.

From 2014 to 2021, Prof Wong was Arthur Lim Professor of Ophthalmology and Medical Director at SNEC, one of the largest tertiary eye hospitals globally, with 100 ophthalmologists across 10 sub-speciality departments, managing >400,000 outpatient visits. Prof Wong was concurrently Deputy Group CEO (Research and Education) and Vice-Dean at SingHealth Duke-NUS Academic Medical Centre, with 30,000 staff and managing >2.5 million outpatient clinical appointments per year. In this role, he lead four cluster-wide offices (Group Research, Group Education, Joint Office of Academic Medicine, Office of Academic Clinical Development), which plan and coordinate clinical and translational research, innovation, enterprise and industry collaboration across 11 hospitals and healthcare institutions, including Singapore General Hospital (ranked #8 best hospital, https://www.newsweek.com/best-hospitals-2020), and 5 national specialty centers (Cancer, Heart, Neuroscience, Eye, Dental). His offices also oversee appointments, promotion and tenure of >2,000 faculty (Asst, Assoc and full Professors) and leads an education enterprise training medical students, residents and fellows, as well as nursing students and a diverse range of allied health professionals (e.g., physiotherapists, pharmacists).

Prior to these roles, Prof Wong was Group Director of Research, SingHealth, Head of the Academic Medicine Research Institute (AMRI), Executive Director of the Singapore Eye Research Institute (SERI), Chairman of the Department of Ophthalmology at National University of Singapore, Head of the Department of Ophthalmology at the University of Melbourne, Australia and Managing Director of the Centre for Eye Research Australia.

Prof Wong is a physician-scientist, and an internationally renowned retinal specialist, with a clinical practice focused on macular and retinal diseases, including diabetic retinopathy and age-related macular degeneration, retinal vascular diseases and myopic macular degeneration. Prof Wong leads an inter-disciplinary research program on epidemiological, translational and clinical research on retinal diseases and ocular imaging. He has published >1500 papers, with papers in the New England Journal of Medicine, the Lancet, JAMA, Annals Internal Medicine, Nature and Nature Medicine. He is Highly Cited Researcher (top 1%, 2018, 2020, 2021, 2022, 2023). He has given >500 invited named, plenary, and symposium lectures, and received >US$50 million in grant funding. He is a two-times recipient of the Singapore Translational Researcher (STaR) Award (2008, 2014), the highest award for senior clinician-scientists.

Research Impact

Prof Wong's research has improved the understanding of the burden and risk factors of diabetic retinopathy, a leading cause of blindness. From 2010, Prof Wong set up the national “telemedicine” screening program for diabetic retinopathy. His research on retinal imaging which have shown that measurements of changes in blood vessels in the retina may be a unique non-invasive test for a person’s cardiovascular risk has led to development of a novel imaging software, now licensed and used by >30 international clinical, research and industry partners. In the past 5 years, his team have led research in artificial intelligence (AI) and digital health. He is Co-Founder of two start-up companies: plano (https://www.plano.co/) and EyRIS (http://eyris.io). For his work on diabetic retinopathy, he was personally featured in a profile the Lancet (https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(11)61075-1/fulltext).


Professional Service

Prof Wong is on the Editorial Boards of Lancet Digital Health, NEJM AI and JAMA-Ophthalmology and previously on Boards of American Journal of Ophthalmology, Diabetes Care, Investigative Ophthalmology and Visual Sciences (IOVS) and British Journal of Ophthalmology, amongst many other journals. He is the current President of the Asia-Pacific Ocular Imaging Society (APOIS) and is Vice-President of the Asia-Pacific Vitreo-Retinal Society (APVRS), an elected Trustee of the Association for Research in Vision and Ophthalmology (ARVO) and Council member of the Asia Pacific Academy of Ophthalmology (APAO) and the Asia-Pacific Teleophthalmology Society (APTOS). He has served on the Executive Committee of the Macula Society, the Board of the International Council of Ophthalmology (ICO), and was past President of the College of Ophthalmologists, Singapore. He is an elected Council member and currently Assistant Master of the Academy of Medicine Singapore. He is on the Board of the National Medical Research Council (NMRC) Singapore and was previously a Council member of the Singapore Medical Council.


Awards & Honors

Prof Wong has been recognized with numerous awards, such as the Commonwealth Health Minister’s Award, the Arnall Patz Medal from the Macula Society, the Alcon Research Institute Award and the Eisenhower Fellowship. He has given numerous named lectures, including the De Ocampo Lecture and the Jose Rizal Medal Lecture, Tano Lecture, the Fred Hollows Lecture, the Sir Runme Shaw Memorial Lecture, and the Sir Norman McAlister Gregg Lecture. He has been recognized as the top researcher from NUS (Outstanding Researcher Award on two occasions, 2004, 2009) and the University of Melbourne (Woodward Medal). He has received the National Outstanding Clinician Scientist Award and the President’s Science Award in 2010, and the President’s Science and Technology Award in 2014, the highest awards for healthcare and scientific contribution in Singapore.

He is an elected Fellow of the Singapore National Academy of Sciences, one of two physicians on the Academy. Prof Wong was elected as an international (foreign) member of U.S. National Academy of Medicine in 2020, and as international (corresponding) fellow of the Australian Academy of Health and Medical Sciences in 2021.

In 2023, Prof Wong was awarded the 16th Beijing “Great Wall Friendship Award” by the People's Government of Beijing Municipality.

1. Li J, Guan Z, Wang J, Cheung CY, Zheng Y, Lim LL, Lim CC, Ruamviboonsuk P, Raman R, Corsino L, Echouffo-Tcheugui JB, Luk AOY, Chen LJ, Sun X, Hamzah H, Wu Q, Wang X, Liu R, Wang YX, Chen T, Zhang X, Yang X, Yin J, Wan J, Du W, Quek TC, Goh JHL, Yang D, Hu X, Nguyen TX, Szeto SKH, Chotcomwongse P, Malek R, Normatova N, Ibragimova N, Srinivasan R, Zhong P, Huang W, Deng C, Ruan L, Zhang C, Zhang C, Zhou Y, Wu C, Dai R, Koh SWC, Abdullah A, Hee NKY, Tan HC, Liew ZH, Tien CS, Kao SL, Lim AYL, Mok SF, Sun L, Gu J, Wu L, Li T, Cheng D, Wang Z, Qin Y, Dai L, Meng Z, Shu J, Lu Y, Jiang N, Hu T, Huang S, Huang G, Yu S, Liu D, Ma W, Guo M, Guan X, Yang X, Bascaran C, Cleland CR, Bao Y, Ekinci EI, Jenkins A, Chan JCN, Bee YM, Sivaprasad S, Shaw JE, Simó R, Keane PA, Cheng CY, Tan GSW, Jia W, Tham YC, Li H, Sheng B, Wong TY*. Integrated image-based deep learning and language models for primary diabetes care. Nat Med. 2024 Oct;30(10):2886-2896.

Link to publication: doi: 10.1038/s41591-024-03139-8

Link to Pubmed: PMID: 39030266


2. Ma WZ, Sheng B, Yang L, Qian J, Liu XX, Li JS, Ouyang D, Wang HB, Atanasov AG, Keane PA, Ma WY, Tham YC, Wong TY*. Evolution of Future Medical AI Models – From Task-Specific, Disease-Centric to Universal Health. New England Journal of Medicine AI 2024; 1 (8).

Link to publication: doi: 10.1056/AIp2400289

Link to Pubmed: N/A


3. Dai L, Sheng B, Chen T, Wu Q, Liu R, Cai C, Wu L, Yang D, Hamzah H, Liu Y, Wang X, Guan Z, Yu S, Li T, Tang Z, Ran A, Che H, Chen H, Zheng Y, Shu J, Huang S, Wu C, Lin S, Liu D, Li J, Wang Z, Meng Z, Shen J, Hou X, Deng C, Ruan L, Lu F, Chee M, Quek TC, Srinivasan R, Raman R, Sun X, Wang YX, Wu J, Jin H, Dai R, Shen D, Yang X, Guo M, Zhang C, Cheung CY, Tan GSW, Tham YC, Cheng CY, Li H, Wong TY*, Jia W. A deep learning system for predicting time to progression of diabetic retinopathy. Nat Med. 2024 Feb;30(2):584-594.

Link to publication: doi: 10.1038/s41591-023-02702-z

Link to Pubmed: PMID: 38177850


4. Cheung CY, Ran AR, Wang S, Chan VTT, Sham K, Hilal S, Venketasubramanian N, Cheng CY, Sabanayagam C, Tham YC, Schmetterer L, McKay GJ, Williams MA, Wong A, Au LWC, Lu Z, Yam JC, Tham CC, Chen JJ, Dumitrascu OM, Heng PA, Kwok TCY, Mok VCT, Milea D, Chen CL, Wong TY*. A deep learning model for detection of Alzheimer's disease based on retinal photographs: a retrospective, multicentre case-control study. Lancet Digit Health. 2022 Nov;4(11):e806-e815.

Link to publication: doi: 10.1016/S2589-7500(22)00169-8

Link to Pubmed: PMID: 36192349


5. Cheung CY, Xu D, Cheng CY, Sabanayagam C, Tham YC, Yu M, Rim TH, Chai CY, Gopinath B, Mitchell P, Poulton R, Moffitt TE, Caspi A, Yam JC, Tham CC, Jonas JB, Wang YX, Song SJ, Burrell LM, Farouque O, Li LJ, Tan G, Ting DSW, Hsu W, Lee ML, Wong TY*. A deep-learning system for the assessment of cardiovascular disease risk via the measurement of retinal-vessel calibre. Nat Biomed Eng. 2021 Jun;5(6):498-508.

Link to publication: doi: 10.1038/s41551-020-00626-4

Link to Pubmed: PMID: 33046867


6. Rim TH, Lee CJ, Tham YC, Cheung N, Yu M, Lee G, Kim Y, Ting DSW, Chong CCY, Choi YS, Yoo TK, Ryu IH, Baik SJ, Kim YA, Kim SK, Lee SH, Lee BK, Kang SM, Wong EYM, Kim HC, Kim SS, Park S, Cheng CY, Wong TY*. Deep-learning-based cardiovascular risk stratification using coronary artery calcium scores predicted from retinal photographs. Lancet Digit Health. 2021 May;3(5):e306-e316.

Link to publication: doi: 10.1016/S2589-7500(21)00043-1

Link to Pubmed: PMID: 33890578



7. Sabanayagam C, Xu D, Ting DSW, Nusinovici S, Banu R, Hamzah H, Lim C, Tham YC, Cheung CY, Tai ES, Wang YX, Jonas JB, Cheng CY, Lee ML, Hsu W, Wong TY*. A deep learning algorithm to detect chronic kidney disease from retinal photographs in community-based populations. Lancet Digit Health. 2020 Jun;2(6):e295-e302.

Link to publication: doi: 10.1016/S2589-7500(20)30063-7

Link to Pubmed: PMID: 33328123


8. Xie Y, Nguyen QD, Hamzah H, Lim G, Bellemo V, Gunasekeran DV, Yip MYT, Qi Lee X, Hsu W, Li Lee M, Tan CS, Tym Wong H, Lamoureux EL, Tan GSW, Wong TY*, Finkelstein EA, Ting DSW. Artificial intelligence for teleophthalmology-based diabetic retinopathy screening in a national programme: an economic analysis modelling study. Lancet Digit Health. 2020 May;2(5):e240-e249.

Link to publication: doi: 10.1016/S2589-7500(20)30060-1

Link to Pubmed: PMID: 33328056


9. Milea D, Najjar RP, Zhubo J, Ting D, Vasseneix C, Xu X, Aghsaei Fard M, Fonseca P, Vanikieti K, Lagrèze WA, La Morgia C, Cheung CY, Hamann S, Chiquet C, Sanda N, Yang H, Mejico LJ, Rougier M-B, Kho R, Thi Ha Chau T, Singhal S, Gohier P, Clermont-Vignal C, Cheng C-Y, Jonas JB, Yu-Wai-Man P, Fraser CL, Chen JJ, Ambika S, Miller NR, Liu Y, Newman NJ, Wong TY*, Biousse V; BONSAI Group. Artificial Intelligence to Detect Papilledema from Ocular Fundus Photographs. N Engl J Med. 2020 Apr 30;382(18):1687-1695.

Link to publication: doi: 10.1056/NEJMoa1917130

Link to Pubmed: PMID: 32286748


10. Sabanayagam C, Banu R, Chee ML, Lee R, Wang YX, Tan G, Jonas JB, Lamoureux EL, Cheng CY, Klein BEK, Mitchell P, Klein R, Cheung CMG, Wong TY*. Incidence and progression of diabetic retinopathy: a systematic review. Lancet Diabetes Endocrinol. 2019 Feb;7(2):140-149.

Link to publication: doi: 10.1016/S2213-8587(18)30128-1

Link to Pubmed: PMID: 30005958


11. Wong TY*, Sun J, Kawasaki R, Ruamviboonsuk P, Gupta N, Lansingh VC, Maia M, Mathenge W, Moreker S, Muqit MMK, Resnikoff S, Verdaguer J, Zhao P, Ferris F, Aiello LP, Taylor HR. Guidelines on Diabetic Eye Care: The International Council of Ophthalmology Recommendations for Screening, Follow-up, Referral, and Treatment Based on Resource Settings. Ophthalmology. 2018 Oct;125(10):1608-1622.

Link to publication: doi: 10.1016/j.ophtha.2018.04.007  

Link to Pubmed: PMID: 29776671


12. Tan GS, Gan A, Sabanayagam C, Tham YC, Neelam K, Mitchell P, Wang JJ, Lamoureux EL, Cheng CY, Wong TY*. Ethnic Differences in the Prevalence and Risk Factors of Diabetic Retinopathy: The Singapore Epidemiology of Eye Diseases Study. Ophthalmology. 2018 Apr;125(4):529-536.

Link to publication: doi: 10.1016/j.ophtha.2017.10.026

Link to Pubmed: PMID: 29217148


13. Ting DSW, Cheung CY, Lim G, Tan GSW, Quang ND, Gan A, Hamzah H, Garcia-Franco R, San Yeo IY, Lee SY, Wong EYM, Sabanayagam C, Baskaran M, Ibrahim F, Tan NC, Finkelstein EA, Lamoureux EL, Wong IY, Bressler NM, Sivaprasad S, Varma R, Jonas JB, He MG, Cheng CY, Cheung GCM, Aung T, Hsu W, Lee ML, Wong TY*. Development and Validation of a Deep Learning System for Diabetic Retinopathy and Related Eye Diseases Using Retinal Images From Multiethnic Populations With Diabetes. JAMA. 2017 Dec 12;318(22):2211-2223.

Link to publication: doi: 10.1001/jama.2017.18152

Link to Pubmed: PMID: 29234807


14. Tan GS, Cheung N, Simó R, Cheung GC, Wong TY*. Diabetic macular oedema. Lancet Diabetes Endocrinol. 2017 Feb;5(2):143-155.

Link to publication: doi: 10.1016/S2213-8587(16)30052-3

Link to Pubmed: PMID: 27496796


15. Wong CW, Yanagi Y, Lee WK, Ogura Y, Yeo I, Wong TY*, Cheung CMG. Age-related macular degeneration and polypoidal choroidal vasculopathy in Asians. Prog Retin Eye Res. 2016 Jul;53:107-139.

Link to publication: doi: 10.1016/j.preteyeres.2016.04.002

Link to Pubmed: PMID: 27094371


16. Ting DS, Cheung GC, Wong TY*. Diabetic retinopathy: global prevalence, major risk factors, screening practices and public health challenges: a review. Clin Exp Ophthalmol. 2016 May;44(4):260-77.

Link to publication: doi: 10.1111/ceo.12696

Link to Pubmed: PMID: 26716602


17. Cheung CY, Ong YT, Ikram MK, Ong SY, Li X, Hilal S, Catindig JA, Venketasubramanian N, Yap P, Seow D, Chen CP, Wong TY*. Microvascular network alterations in the retina of patients with Alzheimer's disease. Alzheimers Dement. 2014 Mar;10(2):135-42.

Link to publication: doi: 10.1016/j.jalz.2013.06.009

Link to Pubmed: PMID: 24439169


18. Wong TY*, Ferreira A, Hughes R, Carter G, Mitchell P. Epidemiology and disease burden of pathologic myopia and myopic choroidal neovascularization: an evidence-based systematic review. Am J Ophthalmol. 2014 Jan;157(1):9-25.e12.

Link to publication: doi: 10.1016/j.ajo.2013.08.010

Link to Pubmed: PMID: 24099276


19. Ding J, Wong TY*. Current epidemiology of diabetic retinopathy and diabetic macular edema. Curr Diab Rep. 2012 Aug;12(4):346-54.

Link to publication: doi: 10.1007/s11892-012-0283-6

Link to Pubmed: PMID: 22585044


20. Lim LS, Mitchell P, Seddon JM, Holz FG, Wong TY*. Age-related macular degeneration. Lancet. 2012 May 5;379(9827):1728-38.

Link to publication: doi: 10.1016/S0140-6736(12)60282-7

Link to Pubmed: PMID: 22559899


21. Yau JW, Rogers SL, Kawasaki R, Lamoureux EL, Kowalski JW, Bek T, Chen SJ, Dekker JM, Fletcher A, Grauslund J, Haffner S, Hamman RF, Ikram MK, Kayama T, Klein BE, Klein R, Krishnaiah S, Mayurasakorn K, O'Hare JP, Orchard TJ, Porta M, Rema M, Roy MS, Sharma T, Shaw J, Taylor H, Tielsch JM, Varma R, Wang JJ, Wang N, West S, Xu L, Yasuda M, Zhang X, Mitchell P, Wong TY*; Meta-Analysis for Eye Disease (META-EYE) Study Group. Global prevalence and major risk factors of diabetic retinopathy. Diabetes Care. 2012 Mar;35(3):556-64.

Link to publication: doi: 10.2337/dc11-1909

Link to Pubmed: PMID: 22301125


22. Cheung N, Mitchell P, Wong TY*. Diabetic retinopathy. Lancet. 2010 Jul 10;376(9735):124-36.

Link to publication: doi: 10.1016/S0140-6736(09)62124-3

Link to Pubmed: PMID: 20580421


23. Rogers SL, McIntosh RL, Lim L, Mitchell P, Cheung N, Kowalski JW, Nguyen HP, Wang JJ, Wong TY*. Natural history of branch retinal vein occlusion: an evidence-based systematic review. Ophthalmology. 2010 Jun;117(6):1094-1101.e5.

Link to publication: doi: 10.1016/j.ophtha.2010.01.058

Link to Pubmed: PMID: 20430447


24. Kawasaki R, Yasuda M, Song SJ, Chen SJ, Jonas JB, Wang JJ, Mitchell P, Wong TY*. The prevalence of age-related macular degeneration in Asians: a systematic review and meta-analysis. Ophthalmology. 2010 May;117(5):921-7.

Link to publication: doi: 10.1016/j.ophtha.2009.10.007

Link to Pubmed: PMID: 20110127


25. Rogers S, McIntosh RL, Cheung N, Lim L, Wang JJ, Mitchell P, Kowalski JW, Nguyen H, Wong TY*; International Eye Disease Consortium. The prevalence of retinal vein occlusion: pooled data from population studies from the United States, Europe, Asia, and Australia. Ophthalmology. 2010 Feb;117(2):313-9.e1.

Link to publication: doi: 10.1016/j.ophtha.2009.07.017

Link to Pubmed: PMID: 20022117


26. Lavanya R, Jeganathan VS, Zheng Y, Raju P, Cheung N, Tai ES, Wang JJ, Lamoureux E, Mitchell P, Young TL, Cajucom-Uy H, Foster PJ, Aung T, Saw SM, Wong TY*. Methodology of the Singapore Indian Chinese Cohort (SICC) eye study: quantifying ethnic variations in the epidemiology of eye diseases in Asians. Ophthalmic Epidemiol. 2009 Nov-Dec;16(6):325-36.

Link to publication: doi: 10.3109/09286580903144738

Link to Pubmed: PMID: 19995197


27. McGeechan K, Liew G, Macaskill P, Irwig L, Klein R, Klein BE, Wang JJ, Mitchell P, Vingerling JR, Dejong PT, Witteman JC, Breteler MM, Shaw J, Zimmet P, Wong TY*. Meta-analysis: retinal vessel caliber and risk for coronary heart disease. Ann Intern Med. 2009 Sep 15;151(6):404-13.

Link to publication: doi: 10.7326/0003-4819-151-6-200909150-00005

Link to Pubmed: PMID: 19755365


28. Lindley RI, Wang JJ, Wong MC, Mitchell P, Liew G, Hand P, Wardlaw J, De Silva DA, Baker M, Rochtchina E, Chen C, Hankey GJ, Chang HM, Fung VS, Gomes L, Wong TY*; Multi-Centre Retina and Stroke Study (MCRS) Collaborative Group. Retinal microvasculature in acute lacunar stroke: a cross-sectional study. Lancet Neurol. 2009 Jul;8(7):628-34.

Link to publication: doi: 10.1016/S1474-4422(09)70131-0

Link to Pubmed: PMID: 19481977


29. Sun C, Wang JJ, Mackey DA, Wong TY*. Retinal vascular caliber: systemic, environmental, and genetic associations. Surv Ophthalmol. 2009 Jan-Feb;54(1):74-95.

Link to publication: doi: 10.1016/j.survophthal.2008.10.003

Link to Pubmed: PMID: 19171211


30. Wong TY*, Cheung N, Tay WT, Wang JJ, Aung T, Saw SM, Lim SC, Tai ES, Mitchell P. Prevalence and risk factors for diabetic retinopathy: the Singapore Malay Eye Study. Ophthalmology. 2008 Nov;115(11):1869-75.

Link to publication: doi: 10.1016/j.ophtha.2008.05.014

Link to Pubmed: PMID: 18584872


31. Wong TY*, Chong EW, Wong WL, Rosman M, Aung T, Loo JL, Shen S, Loon SC, Tan DT, Tai ES, Saw SM; Singapore Malay Eye Study Team. Prevalence and causes of low vision and blindness in an urban malay population: the Singapore Malay Eye Study. Arch Ophthalmol. 2008 Aug;126(8):1091-9.

Link to publication: doi: 10.1001/archopht.126.8.1091

Link to Pubmed: PMID: 18695104


32. Wong TY*, Liew G, Tapp RJ, Schmidt MI, Wang JJ, Mitchell P, Klein R, Klein BE, Zimmet P, Shaw J. Relation between fasting glucose and retinopathy for diagnosis of diabetes: three population-based cross-sectional studies. Lancet. 2008 Mar 1;371(9614):736-43.

Link to publication: doi: 10.1016/S0140-6736(08)60343-8

Link to Pubmed: PMID: 18313502


33. Nguyen TT, Wang JJ, Wong TY*. Retinal vascular changes in pre-diabetes and prehypertension: new findings and their research and clinical implications. Diabetes Care. 2007 Oct;30(10):2708-15.

Link to publication: doi: 10.2337/dc07-0732

Link to Pubmed: PMID: 17595350


34. Mohamed Q, Gillies MC, Wong TY*. Management of diabetic retinopathy: a systematic review. JAMA. 2007 Aug 22;298(8):902-16.

Link to publication: doi: 10.1001/jama.298.8.902

Link to Pubmed: PMID: 17712074


35. Cheung N, Wang JJ, Klein R, Couper DJ, Sharrett AR, Wong TY*. Diabetic retinopathy and the risk of coronary heart disease: the Atherosclerosis Risk in Communities Study. Diabetes Care. 2007 Jul;30(7):1742-6.

Link to publication: doi: 10.2337/dc07-0264

Link to Pubmed: PMID: 17389333


36. Wong TY*, Mitchell P. The eye in hypertension. Lancet. 2007 Feb 3;369(9559):425-35.

Link to publication: doi: 10.1016/S0140-6736(07)60198-6

Link to Pubmed: PMID: 17276782


37. Foong AW, Saw SM, Loo JL, Shen S, Loon SC, Rosman M, Aung T, Tan DT, Tai ES, Wong TY*. Rationale and methodology for a population-based study of eye diseases in Malay people: The Singapore Malay eye study (SiMES). Ophthalmic Epidemiol. 2007 Jan-Feb;14(1):25-35.

Link to publication: doi: 10.1080/09286580600878844

Link to Pubmed: PMID: 17365815


38. Wong TY*, Islam FM, Klein R, Klein BE, Cotch MF, Castro C, Sharrett AR, Shahar E. Retinal vascular caliber, cardiovascular risk factors, and inflammation: the multi-ethnic study of atherosclerosis (MESA). Invest Ophthalmol Vis Sci. 2006 Jun;47(6):2341-50.

Link to publication: doi: 10.1167/iovs.05-1539

Link to Pubmed: PMID: 16723443


39. Wong TY*, Klein R, Islam FM, Cotch MF, Folsom AR, Klein BE, Sharrett AR, Shea S. Diabetic retinopathy in a multi-ethnic cohort in the United States. Am J Ophthalmol. 2006 Mar;141(3):446-455.

Link to publication: doi: 10.1016/j.ajo.2005.08.063

Link to Pubmed: PMID: 16490489


40. Wong TY*, Larsen EK, Klein R, Mitchell P, Couper DJ, Klein BE, Hubbard LD, Siscovick DS, Sharrett AR. Cardiovascular risk factors for retinal vein occlusion and arteriolar emboli: the Atherosclerosis Risk in Communities & Cardiovascular Health studies. Ophthalmology. 2005 Apr;112(4):540-7.

Link to publication: doi: 10.1016/j.ophtha.2004.10.039

Link to Pubmed: PMID: 15808241


41. Wong TY*, Rosamond W, Chang PP, Couper DJ, Sharrett AR, Hubbard LD, Folsom AR, Klein R. Retinopathy and risk of congestive heart failure. JAMA. 2005 Jan 5;293(1):63-9.

Link to publication: doi: 10.1001/jama.293.1.63

Link to Pubmed: PMID: 15632337


42. Wong TY*, Knudtson MD, Klein R, Klein BE, Meuer SM, Hubbard LD. Computer-assisted measurement of retinal vessel diameters in the Beaver Dam Eye Study: methodology, correlation between eyes, and effect of refractive errors. Ophthalmology. 2004 Jun;111(6):1183-90.

Link to publication: doi: 10.1016/j.ophtha.2003.09.039

Link to Pubmed: PMID: 15177969


43. Wong TY*, Klein R, Sharrett AR, Duncan BB, Couper DJ, Klein BE, Hubbard LD, Nieto FJ; Atherosclerosis Risk in Communities Study. Retinal arteriolar diameter and risk for hypertension. Ann Intern Med. 2004 Feb 17;140(4):248-55.

Link to publication: doi: 10.7326/0003-4819-140-4-200402170-00006

Link to Pubmed: PMID: 14970147


44. Wong TY*, Klein R, Nieto FJ, Klein BE, Sharrett AR, Meuer SM, Hubbard LD, Tielsch JM. Retinal microvascular abnormalities and 10-year cardiovascular mortality: a population-based case-control study. Ophthalmology. 2003 May;110(5):933-40.

Link to publication: doi: 10.1016/S0161-6420(03)00084-8

Link to Pubmed: PMID: 12750093


45. Wong TY*, Klein R, Sharrett AR, Manolio TA, Hubbard LD, Marino EK, Kuller L, Burke G, Tracy RP, Polak JF, Gottdiener JS, Siscovick DS. The prevalence and risk factors of retinal microvascular abnormalities in older persons: The Cardiovascular Health Study. Ophthalmology. 2003 Apr;110(4):658-66.

Link to publication: doi: 10.1016/S0161-6420(02)01931-0

Link to Pubmed: PMID: 12689883


46. Wong TY*, Klein BE, Klein R, Knudtson M, Lee KE. Refractive errors, intraocular pressure, and glaucoma in a white population. Ophthalmology. 2003 Jan;110(1):211-7.

Link to publication: doi: 10.1016/s0161-6420(02)01260-5

Link to Pubmed: PMID: 12511368



47. Wong TY*, Klein R, Sharrett AR, Couper DJ, Klein BE, Liao DP, Hubbard LD, Mosley TH; ARIC Investigators. Atheroslerosis Risk in Communities Study. Cerebral white matter lesions, retinopathy, and incident clinical stroke. JAMA. 2002 Jul 3;288(1):67-74.

Link to publication: doi: 10.1001/jama.288.1.67

Link to Pubmed: PMID: 12090864


48. Wong TY*, Klein R, Sharrett AR, Schmidt MI, Pankow JS, Couper DJ, Klein BE, Hubbard LD, Duncan BB; ARIC Investigators. Retinal arteriolar narrowing and risk of diabetes mellitus in middle-aged persons. JAMA. 2002 May 15;287(19):2528-33.

Link to publication: doi: 10.1001/jama.287.19.2528

Link to Pubmed: PMID: 12020333


49. Wong TY*, Klein R, Sharrett AR, Duncan BB, Couper DJ, Tielsch JM, Klein BE, Hubbard LD. Retinal arteriolar narrowing and risk of coronary heart disease in men and women. The Atherosclerosis Risk in Communities Study. JAMA. 2002 Mar 6;287(9):1153-9.

Link to publication: doi: 10.1001/jama.287.9.1153

Link to Pubmed: PMID: 11879113


50. Wong TY*, Klein R, Couper DJ, Cooper LS, Shahar E, Hubbard LD, Wofford MR, Sharrett AR. Retinal microvascular abnormalities and incident stroke: the Atherosclerosis Risk in Communities Study. Lancet. 2001 Oct 6;358(9288):1134-40.

Link to publication: doi: 10.1016/S0140-6736(01)06253-5

Link to Pubmed: PMID: 11597667


51. Wong TY*, Klein R, Klein BE, Tielsch JM, Hubbard L, Nieto FJ. Retinal microvascular abnormalities and their relationship with hypertension, cardiovascular disease, and mortality. Surv Ophthalmol. 2001 Jul-Aug;46(1):59-80.

Link to publication: doi: 10.1016/s0039-6257(01)00234-x

Link to Pubmed: PMID: 11525792