SHI, Xuanling-School of Medicine, Tsinghua University

Research Faculty

SHI, Xuanling

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Tel: +86-10- 62797532
E-mail: shixuanlingsk@tsinghua.edu.cn
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    2008,6-Present Research assistant professor, School of Medicine, Tsinghua University

    2005,6-2008,6 Postdoctoral fellow, Albert Einstein College of Medicine

    2004.6—2005,6 Research assistant professor, Institute of Micr obiology, Chinese Academy of Sciences

    2001.4—2004.6 Postdoctoral fellow, College of Life Sciences, Peking University

    1997.9—2000.6 PhD, Peking Union Medical College

    1993.9—1996.6 MS, Peking Union Medical College

    1988.9—1993.6 MD, West China University of Medical Sciences

Viral Immunology

Antigen antibody interactions of HIV, influenza virus, hepatitis virus and other infectious viruses.

1. Guo D, Shi X, Arledge KC, Song D, Jiang L, Fu L, Gong X, Zhang S, Wang X, Zhang L.A single residue within the V5 region of HIV-1 envelope facilitates viral escape from the broadly neutralizing monoclonal antibody VRC01. J Biol Chem. 2012 Oct 25. [Epub ahead of print]

2. Zuo T, Shi X, Liu Z, Guo L, Zhao Q, Guan T, Pan X, Jia N, Cao W, Zhou B, Goldin M, Zhang L. Comprehensive analysis of pathogen-specific antibody response in vivo based on an antigen library displayed on surface of yeast. J Biol Chem. 2011 Sep 23;286(38):33511-9. Epub 2011 Jul 27.

3. Shang, H., X. Han, X. Shi, T. Zuo, M. Goldin, D. Chen, B. Han, W. Sun, H. Wu, X. Wang, and L. Zhang. Genetic and neutralization sensitivity of diverse HIV-1 ENV clones from chronically infected patients in China. J Biol Chem 286:14531-14541.2011

4. Braun SE, Shi X, Qiu G, Wong FE, Joshi PJ, Prasad VR, Johnson RP. Instability of retroviral vectors with HIV-1-specific RT aptamers due to cryptic splice sites in the U6 promoter. AIDS Res Ther. 2007 Oct 17;4:24.

5. Nie Y*, Wang G*, Shi X*, Zhang H*, Qiu Y, He Z, Wang W, Lian G, Yin X, Du L, Ren L, Wang J, He X, Li T, Deng H, Ding M. Neutralizing antibodies in patients with severe acute respiratory syndrome-associated coronavirus infection. J Infect Dis. 2004 Sep 15;190(6):1119-26. (*: co-first author)