YUAN, Kexin-School of Medicine, Tsinghua University

Neural Engineering

YUAN, Kexin

Contact Us：
Tel: +86-10-62783759
E-mail: kexinyuan@mail.tsinghua.edu.cn
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    Principal Investigator and Associate Professor (with tenure), Tsinghua University

    Education

    State Key Laboratory of Brain and Cognitive Sciences, Institute of Biophysics, Chinese Academy of Sciences, Ph.D., 2006

    Yantai University, B.S., 2001

    Appointments

    2018 – present,Tsinghua University,School of Medicine,Department of Biomedical Engineering,Principal Investigator and Associate Professor(with tenure)

    2012 – 2018,Principal Investigator and Associate Professor

    2006 – 2012,University of California, San Francisco, Postdoctoral Fellow

    2006 – 2008,University of California, Berkeley, Postdoctoral Fellow

Our living environment is full of sensory stimuli, and we have to make appropriate reactions to them to survive. My lab tries to address a central question in neuroscience - how are sensory stimuli represented in the brain and transformed into behaviors? Particularly, we are probing the functional roles of brain regions receiving multimodal sensory inputs, such as certain subsets of the brainstem, midbrain, forebrain and basal ganglia nuclei, because we believe they are the places where sensory information from our environment are integrated and processed to shape our behaviors. We are currently using rodent, and will use non-human primate, animal models and multidisciplinary approaches, including neurophysiological recording, virus-assisted circuit tracing, opto- and chemogenetics, behavioral training, optical imaging and computing. In addition, we are also developing new research tools. In my lab, students with biological and engineering background work collaboratively, creatively and productively.

Selected Publications

1.Cai, Dongqin#; Yue, Yin#; Sue, Xin; Liu, Miaomiao; Wang, Yiwei; You, Ling; Xie, Fenghua; Deng, Fei; Chen, Feng; Luo, Minmin; Yuan, Kexin*; Distinct Anatomical Connectivity Patterns Differentiate Subdivisions of the Nonlemniscal Auditory Thalamus in Mice , Cerebral Cortex, 2019, 29(6): 2437-2454.

2.Xie, Fenghua#; You, Ling#; Cai, Dongqin; Liu, Miaomiao; Yue, Yin; Wang, Yiwei; Yuan, Kexin*; Fast Inhibitory Decay Facilitates Adult-like Temporal Processing in Layer 5 of Developing Primary Auditory Cortex , Cereb Cortex, 2018, 28(12): 4319-4335.

3.Cai, Dongqin#; Han, Rongrong#; Liu, Miaomiao; Xie, Fenghua; You, Ling; Zheng, Yi; Zhao, Limin; Yao, Jun; Wang, Yiwei; Yue, Yin; Schreiner, Christoph E.; Yuan, Kexin*; A Critical Role of Inhibition in Temporal Processing Maturation in the Primary Auditory Cortex , Cereb Cortex, 2018, 28(5): 1610-1624.

4.Yuan, Kexin*; Shih, Jonathan Y.; Winer, Jeffery A.; Schreiner, Christoph E.*; Functional Networks of Parvalbumin-Immunoreactive Neurons in Cat Auditory Cortex , Journal of Neuroscience, 2011, 31(37): 13333-13342.

5.Dorrn, Anja L.#; Yuan, Kexin#; Barker, Alison J.; Schreiner, Christoph E.; Froemke, Robert C.*; Developmental sensory experience balances cortical excitation and inhibition , Nature, 2010, 465(7300): 0-932.