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生物医学工程系

刘鹏

履历

    2012- 至今清华大学医学院生物医学工程系研究员

    2010-2012美国桑迪亚国家实验室博士后

    2004-2009美国加利福尼亚大学伯克利分校生物工程专业博士

    2000-2003清华大学生物化学与分子生物学专业理学硕士

    1998-2000清华大学计算机技术与应用专业工学学士 ( 第二学位 )

    1995-2000清华大学环境科学与工程专业工学学士


研究领域与方向

主要从事微流控与生物芯片方面的研究工作,主要包括:一是基于微流控、纳米和传感器新技术开 发用于临床分子诊断和法医 DNA 检验的微型全分析系统及其关键提取、扩增和检测技术,实现分 子诊断和法医物证分析的自动化、现场化和微小型化;二是开发用于细胞培养、操作和分析的阵 列化微流控技术平台,高通量地实现对细胞表形与基因型的多层次系统化分析,用于干细胞微环境、 药物筛选和单细胞测序等方面的研究工作。

学术荣誉与奖励

关键词

cell sorting and analysis, DNA sequencing, forensic short tandem repeat analysis

代表性论文

1.  Liu, P., Meagher, R.J., Light, Y.K., Yilmaz, S., Chakraborty, R., Arkin, A.P., Hazen, T.C. and Singh, A.K. Microfluidic fluorescence in situ hybridization an d flow cytometry (µFlowFISH) for environmental bacterial detection. Lab on a Chip 11, 2673-2679 (2011).

2.  Liu, P., Scherer, J.R., Greenspoon, S.A., Chiesl, T.N. and Mathies, R.A. Integrated sample cleanup and capillary array electrophoresis microchip for forensic sh ort tandem repeat analysis. Forensic Science International: Genetics 5, 484-492 (2011).

3.  Liu, P., Li, X., Greenspoon, S.A. and Mathies, R.A. Integrated DNA purification, PCR, sample cleanup, and capillary electrophoresis microchip for forensic human identification. Lab on a Chip 11, 1041-1048 (2011).

4.  Thaitrong, N., Liu, P., Briese, T., Lipkin, I.W., Chiesl, T.N., Higa, Y. and Mathies, R.A. Integrated capillary electrophoresis microsystem for multiplex analysis of human respiratory viruses. Analytical Chemistry 82, 10102-10109 (2010).

5.  Scherer, J.R.,* Liu, P.* and Mathies, R. A. Design and operation of a portable scanner for high performance microchip capillary array electrophoresis. Review of Scientific Instruments 81, 113105 (2010). * Joint first authors.

6.  Liu, P. and Mathies, R. A. Integrated microfluidic systems for high-performance genetic analysis. Trends in Biotechnology 27, 572-581 (2009).

7.  Yeung, S.H.I.,* Liu, P.,* Del Dueno, N., Greenspoon, S.A. and Mathies, R.A. Integrated sample cleanup-capillary electrophoresis microchip for high-performance short tandem genetic repeat analysis. Analytical Chemistry 81, 2 10-217 (2009). * Joint first authors.

8.  Liu, P., Yeung, S.H.I., Crenshaw, K.A., Crouse, C.A., Scherer, J.R. and Mathies, R.A. Real-time forensic DNA analysis at a crime scene using a portable microchi p analyzer. Forensic Science International: Genetics 2, 301-309 (2008).

9.  Beyor, N., Seo, T.S., Liu, P. and Mathies, R.A. Immunomagnetic bead-based cell concentration microdevice for dilute pathogen detection. Biomedical Microdevices 10, 909-917 (2008).

10.Liu, P., Seo, T.S., Beyor, N., Shin, K., Scherer, J.R. and Mathies, R.A. Integrated portable PCR-Capillary electrophoresis microsystem for rapid forensic short tandem repeat typing, < em>Analytical Chemistry 79, 1881-1889 (2007).


联系方式

Email: pliu at tsinghua.edu.cn

Phone: +86-10-62798732

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