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生物医学工程系

程京

履历

    1999.03-至今,清华大学生物医学工程系讲席教授、博士生导师

    2000.09-至今,生物芯片北京国家工程研究中心,主任

    1996.12-1999.03,美国Nanogen公司,Principal Scientist

    1996.06-1996.11,美国Pennsylvania大学医学院,研究助理教授

    1988.03-1989.03,英国Strathclyde大学化学系,访问学者

    1986.12-1995.12,西南政法大学司法鉴定中心,助理工程师

    1994.11-1996.06,美国Pennsylvania大学病理及实验室医学系,病理及实验医学,博士后

    1993.04-1994.11,英国Aberdeen大学分子及细胞生物学系,分子及细胞生物学,博士后

    1992.11-1993.03,英国Strathclyde大学化学系,司法生物学,博士后

    1989.03-1992.10,英国Strathclyde大学化学系,司法生物学,博士

    1979.09-1983.07,上海铁道大学(同济大学)电气工程系,电气工程,学士


研究领域与方向

主要从事 DNA 芯片、蛋白芯片、细胞芯片和芯片缩微实验室的研究开发和在健康管理、疾病诊断、 食品安全检测、药物开发中的应用研究,以及依托互联网大数据和人工智能的大健康管理相关研究。


1.  The design and development of biochips: Develop novel biochips including microarrays, microfluidics chips and lab-on-a-chip devices for mutation detection, gene expression, protein analysis, cell assay, etc.

2.  Translational study in using chips for personalized medicine: Emphasize application of biochips for personalized medical applications in oncology, inherited diseases, infectious diseases, reproductive medicine etc.

3.  The study of new detection methods: Interested in developing new labeling and labelless detection technologies.

学术荣誉与奖励

    国家杰出青年基金获得者、教育部长江学者计划特聘教授。

    在Nature Biotechnology,Nature Communications 等杂志上发表SCI收录学术论文153篇,被SCI他人引用9000 余次。2001年作为第一主编,撰编了由美国Harwood Academic 出版社出版的世界上第一部关于生物芯片技术的英文专著《Biochip Technology》。曾两次荣获国家技术发明奖二等奖(2007年、2018年)、树兰医学奖(2018年)、首届转化医学杰出贡献奖(2018年)、黄家驷生物医学工程奖一等奖(2017年)、谈家桢生命科学成就奖(2016年)、中国工程院光华工程科技奖(2014年)、中国首届杰出工程师奖(2014年)、何梁何利科学与技术创新奖(2008年)、第八届中国青年科技奖(2008年)、中国科协求是杰出青年成果转化奖(2004年)、留学回国人员成就奖(2003年)等奖项。

关键词

Medical Biophysics

代表性论文

1.       Dai, P., Huang, L., Wang, J., Gao, X., Qu, C., Chen, X., Ma, F., Zhang, J., Xing, W., Xi, S., Ma, B., Pan, Y., Cheng, X., Duan, H., Yuan, Y., Zhao, L., Chang, L., Gao, R., Liu, H., Zhang, W., Huang, S., Kang, D., Liang, W., Zhang, K., Jiang, H., Guo, L., Zhou, Y., Zhang, W., Lyu, F., JIn, Y., Zhou, Z., Lu, H., Zhang, X., Liu, P., Ke,J., Hao, J., Huang, H., Jiang, D., Ni, X., Long, M., Zhang, L., Qiao, J., Morton, C., Liu, X., Cheng, J., Han, D.

"Concurrent hearing and genetic screening of 180,469 neonates with follow-up in Beijing, China." (2019) The American Journa of Human Genetic, 105(4): 803-812.

 

2.       Xu, Y., Xie, X., Duan, Y., Wang, L., Cheng, Z., Cheng, J. "A review of impedance measurements of whole cells" (2016) Biosensors and Bioelectronics, 77: 824-836.

 

3.       Sun, Y., Huang, Y., Yin, A., Pan, Y., Wang, Y., Wang, C., Du, Y., Wang, M., Lan, F., Hu, Z., Wang, G., Jiang, M., Ma, J., Zhang, X., Ma, H., Ma, J., Zhang, W.,Huang, Q., Zhou, Z., Ma, L., Li, Y., Jiang, H., Xie, L., Jiang, Y., Shi, B., Cheng, J., Shen, H., Wang, L. and Yang, Y. "Genome-wide association study identifies a new susceptibility locus for cleft lip with or without a cleft palate” (2015) Nature Communications, 6: 6414.

 

4.       Guo, H., Liu, H., Mitchelson, K., Rao, H., Luo, M., Xie, L., Sun, Y., Zhang, L., Lu, Ying., Liu, R., Ren, A., Liu, S., Zhou, S., Zhu, J., Zhou, Y., Huang, A., Wei, L., Guo, Y. and Cheng, J. "MicroRNAs-372/373 promote the expression of hepatitis B virus through the targeting of nuclear factor I/B” (2011) Hepetology, 54 (3): 808–819.

 

5.       Wang, L., Zhu, J., Deng, C., Xing, W. and Cheng, J. "An automatic and quantitative on-chip cell migration assay using self-assembled monolayers combined with real-time cellular impedance sensing” (2008) (封面) Lab on a Chip, 8(6): 872-878.

 

6.       Qiao, J., Shao, W., Wei, H., Sun, Y., Zhao, Y., Xing, W., Zhang, L., Mitchelson, K. and Cheng, J. "Novel high-throughput profiling of human transcription factors and its use for systematic pathway mapping” (2008) Journal of Proteome Research, 7(7): 2769-2779.

 

7.       Li, C., Pan, Q., Guo, Y., Li, Y., Gao, H., Zhang, D., Hu, H., Xing, W., Mitchelson, K., Xia, K., Dai, P. and Cheng, J. "Construction of a multiplex allele-specific PCR-based universal array (ASPUA) and its application to hearing loss screening” (2008) Human Mutation, 29(2): 306-314.

 

8.       Guo, Y., Guo, H., Zhang, L., Xie, H., Zhao, X., Wang, F., Li, Z., Wang, Y., Ma, S., Tao, J., Wang, W., Zhou, Y., Yang, W. and Cheng, J. "Genomic analysis of anti-Hepatitis B Virus(HBV) activity by Small Interfering RNA and lamivudine in stable HBV-producing cell” (2005) Journal of Virology, 2005, 79(22): 14392-14403.

 

9.       Du, H., Wu, M., Yang, W., Yuan, G., Sun, Y., Lu, Y., Zhao, S., Du, Q., Wang, J., Yang, S., Pan, M., Lu, Y., Wang, S. and Cheng, J. "Development of miniaturized competitive immunoassays on a protein chip as a screening tool for drugs” (2005) Clinical Chemistry, 51(2): 368-375.

 

10.    Cheng, J., Sheldon, E.L., Wu, L., Uribe, A., Gerrue, L.O., Heller, M.J., Carrino, J. and O‘ Connell, J.P.  "Preparation and hybridization analysis of DNA/RNA from E. coli on microfabricated bioelectronic chips” (1998) (封面) Nature Biotechnology, 16(6): 541-546.

 

11. Cheng,J. and Kricka, L.J. (eds.) Biochip Technology. Harwood Academic Publishers, Pennsylvania, U.S.A.,2001.



联系方式

Email: jcheng@tsinghua.edu.cn

Phone: +86-10-62772239

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